Epigenetically associated colonic mucosal immune- and defense responses in treatment naïve pediatric ulcerative colitis Short title: Epigenetics of untreated UC
نویسندگان
چکیده
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX; Department of Pediatrics, Baylor College of Medicine, USDA/ARS Children’s Nutrition Research Center, Texas Children’s Hospital, Houston, TX; Department of Computer Science, University of Waikato, Hamilton, New Zealand; Department of Pathology, Baylor College of Medicine; Department of Pediatrics, MassGeneral Hospital for Children, Boston, MA; Department of Pediatrics, Charles University and University Hospital Motol, Prague, Czech Republic; Department of Gastroenterology, Baylor College of Medicine, Houston, TX; contributed equally
منابع مشابه
DNA methylation-associated colonic mucosal immune and defense responses in treatment-naïve pediatric ulcerative colitis
Inflammatory bowel diseases (IBD) are emerging globally, indicating that environmental factors may be important in their pathogenesis. Colonic mucosal epigenetic changes, such as DNA methylation, can occur in response to the environment and have been implicated in IBD pathology. However, mucosal DNA methylation has not been examined in treatment-naïve patients. We studied DNA methylation in unt...
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تاریخ انتشار 2015